In industrial synthesis, acetylene reacts with two equivalents of formaldehyde to form 1,4-butynediol. Hydrogenation of 1,4-butynediol gives 1,4-butanediol. It is also manufactured on an industrial scale from maleic anhydride in the Davy process, which is first converted to the methyl maleate ester, then hydrogenated. Other routes are from butadiene, allyl acetate and succinic acid.
1,4-Butanediol seems to have two types of pharmacological actions. The major psychoactive effects of 1,4-butanediol are because it is metabolized into GHB; however there is a study suggesting that 1,4-butanediol may have potential alcohol-like pharmacological effects on its own.
1,4-butanediol, 110-63-4, cas 110-63-4
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1,4-Butanediol 110-63-4, Density 1.0±0.1 g/cm3
1,4-Butanediol 110-63-4, Boiling Point 228.0±0.0 °C at 760 mmHg
1,4-Butanediol 110-63-4, Melting Point 20 °C
1,4-Butanediol 110-63-4, Molecular Formula C4H10O2
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